Browsing by Author "Mapila Mutsai, Oliver, Bakali"

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    Determining the normal Urea, Creatinine and Electrolytes Indices for young Malawian adults
    (Kamuzu University of Health Sciences, 2021-07-15) Mapila Mutsai, Oliver, Bakali
    1.1.Type of Research This will be a cross-sectional descriptive study aimed at establishing the normal Urea, Creatinine and electrolytes indices for young Malawian adults in Mangochi. 1.2.The problem to be studied Most of the medical decisions that are made by the clinicians are arrived at based on the laboratory results. Reference indices or reference intervals act as the guiding tools for the clinicians to make accurate interpretation of the laboratory findings. However, reference values currently being used in most laboratories in African countries including Malawi are adopted from the literature or the reagent inserts accompanying the reagent manuals. These indices are derived from far more distant populations and may not actually be applicable and relevant to Malawian population due to inherit variations such as age, gender, ethnicity and environment including altitude and geo-chemicals among others. 1.3. Objectives The main objective of this study is to establish normal Urea, Creatinine and electrolytes reference indices for young Malawian adults in Mangochi. A total of 50 samples will be collected from the Voluntary, non-remunerated blood donors at Mangochi District Hospital who will meet the inclusion criteria. The samples will be analyzed at the College of Medicine biochemistry laboratory and reference intervals will be established using Epi info data management system. 1.4. Expected findings and dissemination We expect the reference intervals of the Malawian population, Mangochi in particular to be different from other reference intervals provided by machine inserts or those in the literature. The results will be presented to the College faculty and a copy of the results will be submittedto the COMREC and to the COM library. We are also planning to publish the results for public access.