Maternal & Child Health

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Browsing Maternal & Child Health by Author "Blaise Pascal, Furaha Nzanzu"

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    Glycaemic profile of children undergoing anaesthesia (GLYCANA) at Mercy James Centre in Malawi
    (Kamuzu University of Health Sciences, 2021-11-11) Blaise Pascal, Furaha Nzanzu
    Type of study: This will be a cross-sectional observational study of children aged 1 day to 15 years anaesthetised at Mercy James Centre (MJC). Problem: Hypoglycaemia and hyperglycaemia may develop during anaesthesia and surgery in children and can lead to severe adverse clinical outcomes. However, glucose checking is not routinely performed perioperatively in our settings. This may lead to missing children with deranged blood sugar and related complications. No study, as far as we know, has investigated glucose homeostasis in children undergoing surgery in Malawi. Objective of the study: The aim of this study is to assess perioperative glucose levels of the children undergoing anaesthesia in MJC following current anaesthesia protocols. Methodology: Data will be collected for a minimum of 1 month. The sample will be calculated with an online sampling tool. Paediatric patient aged from 1 day to 15 years admitted for surgery at MJC and whose parents or legal guardians will be willing to give written consent will be included in the study. The exclusion criteria will include neonates less than 24 hours old, children coming for examination under anaesthesia and those whose operation will last less than 30 minutes. For each patient, socio-demographic information; pre, intra and postoperative variables will be recorded using a designed data collection form. Anaesthesia chart will be reviewed for data consistency. Data will be analysed using SPSS 26. ANOVA test will be used to compare means. Chi Square test and p-values at level of significance of 5% will be calculated to establish correlations. Expected findings: We expect to find children with deranged glycemia preoperatively mostly hypoglycaemia. We also expected to find children with deranged glycemia postoperatively both hypoglycaemia and hyperglycaemia. Duration of starvation period, types of fluid perioperatively, duration of the surgery may be the major factors associated with the variation of glycemia during anaesthesia. Dissemination: The findings of this study will be presented in one of the meetings at MJC, to Queen Elizabeth Central Hospital (QECH) research committee and to College of Medicine Research and Ethics Committee (COMREC). A manuscript will be submitted for publication in ananaesthesia pair reviewed journal.