Factors associated with utilization of ITNs following immunization with RTS,S/AS01E malaria vaccine in underfive children in Nchalo-Chikwawa

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Date
19-01-22
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Kamuzu University of Health Sciences
Abstract
Type of study The study will be an embedded mixed method cross-sectional study. Problem Malaria is the leading cause of mortality and morbidity in children below the age of five. The pandemic continues to increase morbidity in Africa. The use of RTS, S/AS01E RTS, S malaria vaccine helps to prevent 39% of malaria cases and 29% cases of severe malaria in young children. Since the vaccine is only partially effective, the Ministry of Health (MoH) recommends the use of additional preventive measures, such as indoor spraying, proper diagnosis and the use of ITNs. However, it is not known as to what extent caregivers adhere to these preventive measures after their children have received the malaria vaccine, and whether the use of RTSs will reduce demand for or utilization of ITNs under the assumption that the vaccine is highly protective. Broad objective To determine factors associated with utilization of ITNs in under-five children following RTS’S Malaria Vaccine in under-five children in Nchalo- Chikwawa. Specific objectives: 1. To determine prevalence of ITN use in under five children following malaria vaccination 2. To identify social and economic factors associated with ITN use among malaria vaccinated children. 3. To explore mother’s/guardian views regarding the use of ITNs after their children have received malaria vaccine. An embedded mixed method cross-sectional study. The study will be conducted in Nchalo –Chikwawa District. The study will run from August 2021 to May 2022. Data collection will be in October and December 2021. The plan is to enroll 280 children who have received three or four doses of malaria vaccine, and 24 women (3 FGDs, 8 participants in each group) of women coming to the under-five clinic. One research assistant trained in research ethics and good clinical practice will be recruited to help in data collection. Written informed consent will be sought from all eligible study participants. Data will be collected from perspective of caregivers of children who have received 3 or 4 doses of malaria vaccine on Qualitative data will be collected through FGD with the care givers, face to face while observing Covid -19 preventive measures. Data will be transcribed and imported into NVivo 12 for windows a qualitative data analysis software. Quantitative data will be collected through structured questionaries. STATA will be used for analysis.
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Factors associated with utilization of ITNs
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