Survival rate and determinants of mortality during TB treatment among adult TB - HIV co-infected in-patients at central hospitals in Malawi: a case study of Zomba Central Hospital, version 1.0
| dc.contributor.author | Kazembe, Dickson | |
| dc.date.accessioned | 2023-01-03T14:42:54Z | |
| dc.date.available | 2023-01-03T14:42:54Z | |
| dc.date.issued | 2022-08-05 | |
| dc.description.abstract | EXECUTIVE SUMMARY Research title: Survival rate and determinants of mortality during TB treatment among adult TB - HIV co-infected patients in central hospitals in Malawi: a case study of Zomba Central Hospital Study type: This is a hospital-based quantitative retrospective cohort study design. The study will use secondary data from patients admitted to the TB ward at Zomba Central Hospital from 2017 to 2021. Problem statement: There is limited knowledge on the survival rate and determinant of mortality during TB treatment among adult TB – HIV coinfected in-patients hospitalized in tertiary hospitals in Malawi. Literature shows that the survival rate and risk factors for mortality of TB - HIV co- infected patients differs from place to place even within Sub-Saharan African countries. Furthermore, the determinants of mortality among TB – HIV coinfected patients change with time. Management of TB - HIV co-infected patients present challenges resulting in a reduced survival rate. The response to treatment may be slow in TB – HIV coinfected patients, especially when the patients are severely immune-compromised. Central hospitals provide tertiary health care to patients referred from secondary or primary health care such as district hospitals, and they are in a critical health situation that needs specialized health care that affects their treatment outcomes. However, there are few reported studies on survival rate and determinant mortality among adult TB – HIV coinfected patients hospitalized in tertiary hospitals in Malawi. Objectives of the study Broad objective To assess survival rate and determinants of mortality among hospitalized adult TB - HIV co- infected patients at Zomba Central Hospital. Specific objectives To determine social demographic factors associated with reduced survival rate among hospitalized adult TB - HIV co-infected patients To determine clinical factors associated with reduced survival rate among hospitalized adult TB - HIV co-infected patients To evaluate the probability of surviving hospitalization among TB - HIV co-infected in- patients05-Aug-2022 ii Dickson Kazembe - P.06/22/3674: Expedited protocol version II.0 To assess the trend of survival rate among adult TB - HIV co-infected patients hospitalized at ZCH over 5 years period between 2017 and 2021 Methodology: The study will use a hospital-based quantitative retrospective cohort study design. The study will use secondary data from patients admitted to the TB ward at Zomba Central Hospital from 2017 to 2021. The data will be coded, entered, and cleaned in Microsoft excel 2016 then exported and analyzed using STATA version 16. Expected findings: the researcher expects to find the probability of surviving a duration of hospitalization among adult TB-HIV coinfected patients in central hospitals. The study findings will be helpful to understand the impact of the TB - HIV co-infection that will be used in developing policies in managing the TB - HIV cases in central hospitals as well as used as a basis for future research studies. Dissemination of the results: The final copies of the dissertation will be submitted and made available to KUHEs, ZCH, and TB or/and HIV program stakeholders. In addition, the report of the study will be presented and shared with ZCH management, health professionals, stakeholders, and patients through meetings at the health facility, research conferences, and peer-reviewed journals | en_US |
| dc.description.sponsorship | Self | en_US |
| dc.identifier.uri | http://rscarchive.kuhes.ac.mw/handle/20.500.12988/1109 | |
| dc.language.iso | en | en_US |
| dc.relation.ispartofseries | P.06/22/3674; | |
| dc.title | Survival rate and determinants of mortality during TB treatment among adult TB - HIV co-infected in-patients at central hospitals in Malawi: a case study of Zomba Central Hospital, version 1.0 | en_US |
| dc.type | Plan or blueprint | en_US |