African Surgical Outcomes Study in Paediatric patients (ASOS-Paeds)
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Date
2022-06-15
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kamuzu University of Health Sciences
Abstract
TYPE OF STUDY
Multi-centre prospective observational cohort study.
PROBLEM
Access to safe surgery is a basic human right. This is highlighted by the work of the Lancet Commission on Global Surgery.There is a burden of surgical disease in the paediatric surgical population with a large need. In Africa, children comprise a significant proportion of the population with approximately 50% of the population being ≤19 years old.
Limited
Limited data from Africa suggests the risk factors for, incidence and outcomes associated with paediatric
surgical complications differ from HICs. The African Surgical Outcomes Study (ASOS) has described surgical outcomes in adult patients in Africa. There is a need to determine the burden of the complications in paediatric surgical patients in Africa, and the risk factors for and the type of complications experienced.
STUDY OBJECTIVES
The main objective of this study is to confirm the incidence of in-hospital postoperative complications up to 30 days post-surgery in paediatric surgical patients aged < 18 years in Africa. In paediatric
surgical patients < 18 years in Africa:
1. To determine the in-hospital postoperative complications including mortality
up to 30 days post-surgery,
2. To evaluate the incidence of intraoperative critical incidents,
3. To assess the association between pre-operative, intra-operative and
facility factors with postoperative complications including death.
METHODS
An African multi-centre prospective observational cohort study of All consecutive paediatric patients aged < 18 years admitted to participating hospitals undergoing elective and non-elective surgery .
The primary outcome measure is in-hospital postoperative complications. Obstetric surgery will be excluded. The primary outcome measure is in-hospital postoperative complications censored at 30 days post operatively. This study is expected to start in March 2022.
EXPECTED FINDINGS AND DISSEMINATION
We expect the outcomes to be potentially worse in Africa, because firstly, there is a limited workforce, and secondly there are limited intensive care facilities and critical care resources across Africa to provide sufficient care.
A report of the research findings will be submitted to the College of Medicine Research and Ethics Committee, the College of Medicine Library, the Health Sciences research committee, the University research and publication committee, the Lancet Commission and the Ministry of Health
2. Summary Short title ASOS-Paeds
Methodology A prospective international, multi-centre, African observational study
Research sites Hospitals undertaking paediatric surgery in participating African
Objective
To confirm the incidence of in-hospital postoperative complications up to
30 days post-surgery in paediatric surgical patients aged < 18 years in Africa.
Number of 7000 patients
Inclusion All consecutive paediatric patients aged < 18 years admitted to
criteria participating hospitals undergoing elective and non-elective surgery
Exclusion Obstetric surgery
Description
Keywords
African Surgical Outcomes Study in Paediatric patients