Assessing immunosuppressive status in HIV clients with cervical cancer at Queen Elizabeth Central Hospital, Gynaecology Unit
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Date
2022-04-11
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kamuzu University of Health Sciences
Abstract
Type of study
Retrospective folder review study.
Problem
Women living with HIV have increased risk of developing cervical cancer which is associated
with an increase in mortality rate. Malawi being one of the countries with high HIV prevalence
rate, this study wants to determine the immunosuppressive status of HIV positive women with
cervical cancer.
Broad objective
• To assess immunosuppressive status in HIV clients with cervical cancer
Specific Objectives
• To determine the effect that cervical cancer has on HIV viral load status and CD4 count.
• To explore association of viral load status in HIV patients with cervical cancer with age,
cancer stage, socio-economic status and level of education.
• To assess how ART adherence, affect HIV viral load status in HIV patients with cervical
cancer.
methodology
This will be a retrospective folder review study. A total of 87 HIV clients with cervical cancer
files will be obtained from QECH, gynecology department. A simple random sampling method
will be used to sample the files. Variables such as age socio-economic status, level of education,
stage of cancer, ART intake will be collected through a questionnaire. CD4 count and Viral load
data between 2016-2021 will be collected from the files of the selected clients.
Expected findings
The viral load of HIV patients with cervical cancer will increase while CD4 will decrease. This
is because HIV and AIDS patients have reduced immunity and the cancer lowers the immunity
further hence the virus replicates rapidly. PowerPoint presentation will be done at Kamuzu
College of Health Sciences (KUHeS) and at any designated Research Conferences. A final copy
will be sent to the research supervisor(s), QECH, COMREC, Head of department and the
Library. Manuscripts will also be prepared and be submitted at journal for publications.
11-Apr-2022
Assessing immunosuppressive status in HIV clients with cervical cancer at Gynecology unit,
QECH, Blantyre; Malawi V2.0 21 March 2022