Evaluation of gestation Diabetes Mellitus at Zomba Central Antenatal Hospital Clinic
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Date
2021-01-13
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Kamuzu University of Health Sciences
Abstract
Gestational Diabetes Mellitus (GDM) was earlier defined as “hyperglycemia first
recognized during pregnancy” and has more recently been described by the
American Diabetes Association as diabetes diagnosed during pregnancy that is
not clearly overt diabetes. GDM is associated with a wide range of adverse
outcomes for women and their babies. Having GDM can increase the risk of high
blood pressure during pregnancy. It can also increase the risk of having a large
baby that needs to be delivered by cesarean section. Therefore results of this
research can help in development of policies, management of antenatal mothers
and used as basis for other studies. The objective of the study is to evaluate the
prevalence rate of GDM and determine risk factors. This will be a cross sectional
prospective study where by 300 participants shall be randomly selected through
convenience sampling method. Women of 24-28 weeks gestation who pass the
inclusion and exclusion criteria and have given their written consent shall be
included in the study and their height, weight and age shall be recorded.
Thereafter 75-g Oral Glucose Tolerance Test shall be performed in the morning
after an overnight fast of at least 8 hours. The diagnosis of GDM is made if at
least two of the following is met or exceeded i) fasting: 95 mg/dl ii) 1 hour: 180
mg/dl iii) 2 hour: 155 mg/dl. After centrifuging the blood sample in an
anticoagulant tube, plasma shall be put in a BS 360 E Chemistry Analyzer to test
for the client’s plasma glucose level. We expect a low GDM prevalence rate and
association between GDM and maternal obesity as well as age. To compare the
proportion of GDM across the age groups, Body Mass Index and gravida Chi Square
test shall be used. Results of the research shall be available to College of
Medicine Research Ethics Committee, Zomba Central Hospital and college of
medicine library. Ethical clearance for this research project shall be sought from
College of Medicine Research Ethics Committee.
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Research Subject Categories::MEDICINE