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Browsing Protocol by Subject "Vitamin C and D supplementation in non severe COVID-19 patients"

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    Supplementation tendencies of vitamin C and D among non-severe COVID-19 patients in Blantyre, Malawi
    (2021-11-18) Katundu, Kondwani
    Study Type: Retrospective cross-sectional quantitative study. Background: Low blood Vitamin C and D have been associated with the severity of Coronavirus disease 2019 (COVID-19). The practice of vitamin supplementation among individuals with non-severe COVID- 19 disease appears to be common, but the frequency and dose of these vitamins among this population group has not been well evaluated in Malawi. Study Objectives: This study aims to determine prevalence and dose of supplementation of the vitamin C and D among non-severe COVID-19 patients in Blantyre, Malawi. Methods: We will conduct a retrospective study in randomly selected recovered non-severe COVID-19 adults (n=150) in Blantyre, Malawi who had a COVID-19 infection between January and September 2021. We will acquire information on the frequency, dose and duration of vitamin C and D supplementation during an episode of the non-severe COVID-19. Sample-size: The sample size for the study will be 150 participants was calculated to detect at least 40% frequency use of vitamin C and D supplementation at a power of 80% and 95% confidence interval. Outcomes and definitions: Vitamin C and D supplementation will be considered as any pharmacological form of the vitamins taken orally or parenterally at least at one point during the sickness episode of nonsevere COVID-19 infection. The prevalence of supplementation, the mean dose and the duration of supplementation will be calculated. Expected findings and dissemination: We expect at least 50% use of vitamin C and D supplementation in individuals with non-severe COVID-19. The results once analysed will be published in an international scientific journal and will be presented both at local and regional or international conferences. Published results will also be submitted to the Malawi Liverpool Welcome Trust Clinical Research Programme, College of Medicine Research and Ethics Committee (COMREC), Kamuzu University of Health Sciences Library, Blantyre District Health and Social Services Office and Queen Elizabeth Central Hospital