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- ItemRestrictedInvestigating factors associated with puerperal sepsis and its implications in mothers admitted to maternity ward at Mangochi District Hospital(Kamuzu University of Health Sciences, 2021-10-08) Mambulu, Chitaukali ChifundoType of study: The study will use mixed approach research methods; qualitative and quantitative study. It will investigate the associated factors that may predispose to puerperal sepsis and its implications in mothers admitted to maternity ward at Mangochi District Hospital Statement of the problem: Puerperal sepsis contributes to 15% % of the maternal deaths that occur annually globally and contribute to even more maternal deaths in some low income countries like Malawi. However, puerperal sepsis is preventable if maternal mothers are well taken care of, hence need to establish associated factors to puerperal sepsis and its implications to mothers in order to prevent its occurrence and implications. Objectives: Broad objective: To investigate factors associated with puerperal sepsis and its implications in mothers admitted to maternity ward at Mangochi District Hospital Specific objectives: 1. To explore health care factors associated with puerperal Sepsis to mothers admitted to maternity department at Mangochi District Hospital 2. To determine maternal factors associated with puerperal sepsis at Mangochi District Hospital: Strategy for optimizing identification of associated factors to puerperal sepsis 3. To assess effects of puerperal sepsis on mothers. Methodology: The study will use mixed approach research method. This will be quantitative and qualitative through exploratory and descriptive study to investigate factors associated with puerperal sepsis. The expected sample size for qualitative data will be taken through Key Informants Interviews for 15 participants from the health care workers and this will depend on saturation. Quantitative data will be collected retrospectively from case files of mothers who were diagnosed with puerperal sepsis and were admitted in maternity ward. The expected sample size will be determined by the number of case files available. The sample size has been determined from the total number of files for the target population in the three years which is 440 case files. Using Raosoft, at 95% CI, sampling error of 5% and response distribution of 50%, the minimum desired sample size is 206 files. Proportionate samples will be taken for each year with the multiplication factor that was obtained by dividing total number of files in each year by total number of files for the whole 3 year period as follows: 0.67, 0.15, and 0.18 for 2018/19, 2019/20 and 2020/21 fiscal years respectively giving respective samples of 138, 31 and 37 case files. Using stratified consecutive sampling technique for each year, files will be selected. This will be done using medical extract form. The data will be verified and then entered into a Microsoft Excel file and there-after be imported into STATA Version 14.1 for cleaning and further analysis. For qualitative data, consistency will be maintained by listening to audio recorded KIIs. The verified data will be stored in a password protected file in a USB flash disk, computer and will be backedup in an external driver. Expected findings and dissemination. The research will be conducted on academic requirement to the award of Master of Science Global Health Implementation. Therefore, some copies will be submitted for marking at University of Malawi, College of Medicine. The final dissertation document will be submitted to the College of Medicine Research and Ethics Committee (COMREC) and the College of Medicine Library (COM). The Health Science Research Committee and The University Research and Publication committee through the COMREC secretariat. Furthermore, the intention of the researcher is to take the results and present to Mangochi District Council through Mangochi District Executive Committee (DEC) and the copy will be submitted to the District Health Management Team (DHMT) for Mangochi DHO through Mangochi Research and Ethics Committee. Recommendations will be made to the stakeholders and partners through Mangochi DHO on any improvements that might be suggested to improve the precision of puerperal sepsis.
- ItemRestrictedSeverity of menopause symptoms and coping mechanisms among women in Blantyre, Malawi(Kamuzu University of Health Sciences, 2021-11-09) Kaliati Nyalubwe, ThokozaniType of study This will be a mixed method study. Introduction/background Menopause is a normal physiological event in the life of every woman who lives beyond the age of 52. It is a key transition point of biological and social development which is associated with a wide variety of symptoms which can be very distressing and have considerable effects in a woman’s physical and social life. Problem statement/ justification With global increase in life expectancy issues to do with adult health for example menopause are becoming an area of public health concern. However, to the best of our knowledge there is currently very limited data on menopause in Malawi. Conducting this research will help to contribute towards understanding menopause related issues among women in Malawi and help in establishing contextualized and evidence-based management of these symptoms. Objectives The broad objective is to evaluate the severity of menopause symptoms and the associated coping mechanisms among women in Blantyre, Malawi. The specific objectives are; to determine the prevalence and severity of menopause symptoms among women, to asses knowledge of menopause among women, to assess coping mechanisms of women with menopause symptoms, and finally to describe the effect of menopause symptoms on healthrelated quality of life Methodology This will be a mixed method study in which convergent mixed method study design will be used. The study population are women aged 45 – 59 of which the total sample size is 268 women for the quantitative data and 20 women for the qualitative data. Quantitative data will be analyzed using STATA while thematic analysis and QSR Nvivo software will be used for Qualitative data. Expected Findings and Dissemination We anticipate to find a high prevalence of vasomotor symptoms and a low reporting rate of menopause symptoms among those with low academic and economic status. On experiences of women with menopause symptoms we anticipate to find a reduced sense of femineity, and negative impact on daily activities as seen in studies elsewhere. A dissertation will be compiled and submitted to the department of Obstetrics and Gynaecology, the College of medicine library, College of Medicine Research and Ethics Committee and Blantyre DHO. A presentation will be made to the Association of Obstetrics and Gynaecology Conference and Blantyre district health office and on the findings of the study. A manuscript will be prepared and submitted for publication in a peer reviewed journal.